VOLUME 3 , ISSUE 5 ( September-October, 2024 ) > List of Articles
Siktha Purkait, Sudipto Chakraborty, Swagatam Sengupta, Swapna Skaria, Arpan Chakraborty, Ritwik Ghosh
Keywords : Autoimmune hepatitis, Case report, Dengueviridae, Hepatitis E, Secondary hemophagocytic lymphohistiocytosis syndrome, Scrub typhus, Systemic inflammatory response, Tropical coinfection
Citation Information : Purkait S, Chakraborty S, Sengupta S, Skaria S, Chakraborty A, Ghosh R. Triple Tropical Coinfection: A Therapeutic and Diagnostic Challenge—Case Report. 2024; 3 (5):136-138.
DOI: 10.5005/jp-journals-11006-0129
License: CC BY-NC 4.0
Published Online: 27-08-2024
Copyright Statement: Copyright © 2024; The Author(s).
Aim and background: Tropical infections have a high prevalence in India. Mostly, coinfection with more than one tropical infection makes the diagnosis difficult and increases mortality and morbidity. To increase more awareness regarding tropical infections which can turn into life threatening situations and the need for aggressive management for that. Case description: We present a case of a 51-year-old lady admitted with vomiting and diarrhea, which rapidly progressed into sepsis and multiorgan dysfunction. Blood investigations showed coinfection with hepatitis E, scrub typhus, and dengue. She was treated aggressively with all conservative and interventional measures. Conclusion: Despite our best efforts, she had a persistent high-grade fever, severe anemia, thrombocytopenia, and markedly increased liver enzymes with raised D-dimer, fibrinogen, and ferritin, leading to secondary hemophagocytic lymphohistiocytosis (HLH) syndrome. She succumbed to the illness ultimately. Clinical significance: triple coinfection of dengue, hepatitis E, and scrub typhus, which, to our knowledge, has not been previously reported in the literature, making it an exceptionally rare presentation.
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