Indian Journal of Critical Care Case Report

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VOLUME 3 , ISSUE 4 ( July-August, 2024 ) > List of Articles


Role of Extracorporeal Treatment in Barbiturate Poisoning: A Case Report

Hemal N Shah, Ashish Jain, Mohit Somani, Priyamvada Gupta, Srishti S Jain, Ravi Jain

Keywords : Case report, Extracorporeal treatment, Extracorporeal treatment in poisoning, Intermediate hemodialysis, Severe barbiturate poisoning

Citation Information : Shah HN, Jain A, Somani M, Gupta P, Jain SS, Jain R. Role of Extracorporeal Treatment in Barbiturate Poisoning: A Case Report. 2024; 3 (4):105-108.

DOI: 10.5005/jp-journals-11006-0113

License: CC BY-NC 4.0

Published Online: 21-06-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Barbiturates are a class of sedative and hypnotic drugs. These are commonly used as antiepileptics and anesthetic agents now. Current usage of sedatives in India is about 1.08%, and the abuse is about 0.11%. Barbiturate overdose or poisonings can lead to severe central nervous system depression, potentially life-threatening respiratory depression, and may lead to respiratory arrest. Treatment in the majority of cases of barbiturate poisoning is artificial ventilation and other supportive therapies. Extracorporeal treatments (ECTRs) are required in only 0.1% of cases of poisoning. There is a lack of prospective intervention studies for obvious ethical reasons; however, the ECTR in poisoning (EXTRIP) workgroup recommends the use of ECTRs in severe barbiturate overdose/poisoning.

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