Diagnosis of infective endocarditis (IE) remains a clinical challenge. Transthoracic echocardiogram (ECHO) (TTE) and positron emission tomography (PET) scans have limitations. We report this case of endocarditis where two-dimensional (2D) ECHO and PET scan were nondiagnostic on initial evaluation, and the organism grown on blood culture was probably misidentified. The patient was subsequently diagnosed with mitral valve endocarditis and was started on definitive antimicrobial therapy.
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