Hypereosinophilic Syndrome Presenting with Unusual Triad of Immune Thrombocytopenic Purpura, Cerebral Venous Sinus Thrombosis, and Eosinophilic Pneumonia: A Case Report

Velmurugan Selvam; NVSN Prasant; Steve Thomas

doi:10.5005/jp-journals-11006-0122

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Hypereosinophilic Syndrome Presenting with Unusual Triad of Immune Thrombocytopenic Purpura, Cerebral Venous Sinus Thrombosis, and Eosinophilic Pneumonia: A Case Report

Velmurugan Selvam, NVSN Prasant, Steve Thomas

Keywords : Case report, Cerebral vein thrombosis, Deep vein thrombosis, Eosinophilia, Hypereosinophilic syndrome

Citation Information : Selvam V, Prasant N, Thomas S. Hypereosinophilic Syndrome Presenting with Unusual Triad of Immune Thrombocytopenic Purpura, Cerebral Venous Sinus Thrombosis, and Eosinophilic Pneumonia: A Case Report. 2024; 3 (4):87-90.

DOI: 10.5005/jp-journals-11006-0122

License: CC BY-NC 4.0

Published Online: 21-06-2024

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Abstract

Hypereosinophilic syndrome (HES) has substantial clinical heterogeneity and leads to any organ dysfunction and can be fatal without timely treatment. HES is associated with an extremely poor prognosis, with the survival rate at 60 days after intensive care unit (ICU) admission around 20%. A high index of suspicion is needed for timely diagnosis and early initiation of treatment to improve outcomes. Treatment strategies are aimed at symptom control and limiting end-organ damage by lowering blood eosinophils. The combination of immune thrombocytopenic purpura (ITP), deep vein thrombosis (DVT), and cerebral venous sinus thrombosis (CVST) in the setting of eosinophil-related diseases has seldom been reported. Here, we report a case of a young female who developed eosinophilic pneumonia, DVT, CSVT, and ITP managed successfully with steroids, intravenous immunoglobulin, and anticoagulation.

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