Indian Journal of Critical Care Case Report

Register      Login

VOLUME 2 , ISSUE 5 ( September-October, 2023 ) > List of Articles


Neuromelioidosis Presenting as Cerebral Venous Thrombosis Requiring Emergency Decompressive Craniectomy and Prolonged Neurointensive Care

Nithya Panangadan, Ramanan Rajagopal, Mohanaselvi Sivaraman

Keywords : Burkholderia pseudomallei, Case report, Diagnosis, Neuromelioidosis

Citation Information : Panangadan N, Rajagopal R, Sivaraman M. Neuromelioidosis Presenting as Cerebral Venous Thrombosis Requiring Emergency Decompressive Craniectomy and Prolonged Neurointensive Care. 2023; 2 (5):132-134.

DOI: 10.5005/jp-journals-11006-0071

License: CC BY-NC 4.0

Published Online: 27-10-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Cerebral sinus venous thrombosis (CSVT) is a rare form of venous thromboembolism. CSVT represents almost 0.5–3% of all types of strokes, affecting predominantly younger people. Neuromelioidosis presenting as CSVT is a rare entity and requires a high index of suspicion, combined neurological, neurosurgical, neurointensive care, and infectious disease (ID) inputs along with appropriate and prompt antibiotic cover for improved outcomes. The role of decompressive craniectomy, antibiotic therapy, and duration have been discussed in brief. A rare case of neuromelioidosis presenting as CSVT requiring emergency decompressive craniectomy and prolonged neurointensive care with rehabilitative therapy has been discussed.

  1. Kang G, Rajan DP, Ramakrishna BS, et al. Melioidosis in India. Lancet Lond Engl 1996;347(9014):1565–1566. DOI: 10.1016/s0140-6736(96)90723-0
  2. Deuble M, Aquilina C, Norton R. Neurologic melioidosis. Am J Trop Med Hyg 2013;89(3):535–539. DOI: 10.4269/ajtmh.12-0559
  3. Koshy M, Jagannati M, Ralph R, et al. Clinical manifestations, antimicrobial drug susceptibility patterns, and outcomes in melioidosis cases, India. Emerg Infect Dis 2019;25(2):316–320. DOI: 10.3201/eid2502.170745
  4. Naik S, Bhoi SK, Jha M, et al. Craniospinal mri findings in neuromelioidosis. Neurol India 2023;71(1):113–118. DOI: 10.4103/0028-3886.370442
  5. Jabeen S, Saini J, Mishra T, et al. Neuromelioidosis presenting as a stroke-like syndrome. Neurol Clin Pract 2021;11(4):e589–591. DOI: 10.1212/CPJ.0000000000000933
  6. Ekka AS, Mohideen M, Kesavan S. Neuromelioidosis masquerading as acute demyelinating encephalomyelitis. Indian Pediatr 2017;54(12):1054–1055. DOI: 10.1007/s13312-017-1212-1
  7. Vithoosan S, Kumarasiri A, Vithanage NM, et al. Case report long segment myelitis secondary to neuro melioidosis. BMC Neurol 2022;22(1):387. DOI: 10.1186/s12883-022-02917-6
  8. Niyasom S, Sithinamsuwan P, Udommongkol C, et al. Dural sinus thrombosis in melioidosis: the first case report. J Med Assoc Thai 2006;89(2):242–247. PMID: 16579013.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.