Extracorporeal Membrane Oxygenation as a Rescue Support in Autologous Hematopoietic Stem Cell Transplant-associated Peri-engraftment Syndrome: A Case Report
Sanjay Chaudhary, Gunjan Mundhra, Manoj Ghimire, Rabi Shrestha, Subekshya Khadka, Devang K Sanghavi, Anirban Bhattacharyya, Pramod Guru
Citation Information :
Chaudhary S, Mundhra G, Ghimire M, Shrestha R, Khadka S, Sanghavi DK, Bhattacharyya A, Guru P. Extracorporeal Membrane Oxygenation as a Rescue Support in Autologous Hematopoietic Stem Cell Transplant-associated Peri-engraftment Syndrome: A Case Report. 2023; 2 (4):106-109.
Introduction: Extracorporeal life support (ECLS) is often used as a salvage therapy for respiratory failure refractory to conventional interventions, but its use in immunosuppressed states, including hematopoietic stem cell transplant (HSCT) has been considered a relative contraindication due to increased risk of complications and high mortality.
Case description: We present the case of a 49-year-old male with multiple myeloma who developed peri-engraftment respiratory distress syndrome (PERDS) and Pneumocystis jirovecii pneumonia (PJP) following HSCT and was successfully managed with two runs of venovenous extracorporeal membrane oxygenation (VV-ECMO).
Conclusion: If used judiciously, ECMO can be an effective support strategy in carefully selected immunocompromised patient populations.
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