Indian Journal of Critical Care Case Report

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VOLUME 2 , ISSUE 4 ( July-August, 2023 ) > List of Articles


Extracorporeal Membrane Oxygenation as a Rescue Support in Autologous Hematopoietic Stem Cell Transplant-associated Peri-engraftment Syndrome: A Case Report

Sanjay Chaudhary, Gunjan Mundhra, Manoj Ghimire, Rabi Shrestha, Subekshya Khadka, Devang K Sanghavi, Anirban Bhattacharyya, Pramod Guru

Keywords : Autologous hematopoietic stem cell transplant, Case report, Extracorporeal membrane oxygenation, Jirovecii pneumonia, Peri-engraftment respiratory distress syndrome, Pneumocystis

Citation Information : Chaudhary S, Mundhra G, Ghimire M, Shrestha R, Khadka S, Sanghavi DK, Bhattacharyya A, Guru P. Extracorporeal Membrane Oxygenation as a Rescue Support in Autologous Hematopoietic Stem Cell Transplant-associated Peri-engraftment Syndrome: A Case Report. 2023; 2 (4):106-109.

DOI: 10.5005/jp-journals-11006-0067

License: CC BY-NC 4.0

Published Online: 18-08-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Introduction: Extracorporeal life support (ECLS) is often used as a salvage therapy for respiratory failure refractory to conventional interventions, but its use in immunosuppressed states, including hematopoietic stem cell transplant (HSCT) has been considered a relative contraindication due to increased risk of complications and high mortality. Case description: We present the case of a 49-year-old male with multiple myeloma who developed peri-engraftment respiratory distress syndrome (PERDS) and Pneumocystis jirovecii pneumonia (PJP) following HSCT and was successfully managed with two runs of venovenous extracorporeal membrane oxygenation (VV-ECMO). Conclusion: If used judiciously, ECMO can be an effective support strategy in carefully selected immunocompromised patient populations.

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