Indian Journal of Critical Care Case Report

Register      Login

VOLUME 2 , ISSUE 3 ( May-June, 2023 ) > List of Articles

CASE REPORT

Opsoclonus-myoclonus-ataxia Syndrome Associated with Dengue Fever: A Case Report

Bhavinkumar Patel, Atul Jani, Nimesh Patel, Chetan Trivedi

Keywords : Dengue, Intravenous immunoglobulin, Opsoclonus-myoclonus-ataxia syndrome, Steroids

Citation Information : Patel B, Jani A, Patel N, Trivedi C. Opsoclonus-myoclonus-ataxia Syndrome Associated with Dengue Fever: A Case Report. 2023; 2 (3):64-65.

DOI: 10.5005/jp-journals-11006-0050

License: CC BY-NC 4.0

Published Online: 26-06-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Abstract

Opsoclonus-myoclonus-ataxia syndrome (OMAS) is a rare neurological disorder characterized by irregular multidirectional eye movements, myoclonus, cerebellar ataxia, sleep disturbances, and cognitive dysfunction. Although most commonly occurring as a paraneoplastic syndrome, this condition has occasionally been described following infectious illnesses. This article reports a rare case of OMAS in association with dengue virus infection. This report represents an unusual clinical syndrome associated with a viral infection and reinforces the need for clinical vigilance with regard to neurological syndromes in the context of emerging arboviruses.


HTML PDF Share
  1. Kinsbourne M. Myoclonic encephalopathy of infants. J Neurol Neurosurg Psychiatry 1962;25(3):271–276. DOI: 10.1136/jnnp.25.3.271
  2. Altman AJ, Baehner RL. Favorable prognosis for survival in children with coincident opso-myoclonus and neuroblastoma. Cancer 1976;37(2):846–852. DOI: 10.1002/1097-0142(197602)37:2<846::aid-cncr2820370233>3.0.co;2-l
  3. Digre KB. Opsoclonus in adults. Report of three cases and review of the literature. Arch Neurol 1986;43(11):1165–1175. DOI: 10.1001/archneur.1986.00520110055016
  4. Markakis I, Alexiou E, Xifaras M. Opsoclonus-myoclonus-ataxia syndrome with autoantibodies to glutamic acid decarboxylase. Clin Neurol Neurosurg 2008;110(6):619–621. DOI: 10.1016/j.clineuro.2008.03.005
  5. Pranzatelli MR, Tate ED, McGee NR. Demographic, clinical, and immunologic features of 389 children with opsoclonus-myoclonus syndrome: a cross-sectional study. Front Neurol 2017;8:468. DOI: 10.3389/fneur.2017.00468
  6. Kurian M, Lalive PH, Dalmau JO, et al. Opsoclonus-myoclonus syndrome in anti-N-methyl-D-aspartate receptor encephalitis. Arch Neurol 2010;67(1):118–121. DOI: 10.1001/archneurol.2009.299
  7. Bhalodiya D, Rathore C, Gutpa V, et al. “Dancing eye, dancing feet” in cerebral malaria: a rare association. Neurol India 2018;66(2):543–545. DOI: 10.4103/0028-3886.227326
  8. Motiani R, Agrawal S, Saifee AA. Opsoclonus-ataxia, as an unusual presentation of malaria. Neurol India 1991;39:39–40.
  9. Rosario MSD, Giovanetti M, Jesus PAPD, International Journal of Infectious Diseases 2018;75:11–14.
  10. Desai SD, Gandhi FR, Vaishnav A. Opsoclonus myoclonus syndrome: A rare manifestation of dengue infection in a child. J Pediatr Neurosci 2018;13(4):455–458. DOI: 10.4103/JPN.JPN_55_18
  11. Verma R, Sharma P, Garg RK, et al. Neurological complications of dengue fever: Experience from a tertiary center of north India. Ann Indian Acad Neurol 2011;14(4):272–278. DOI: 10.4103/0972-2327.91946
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.