Indian Journal of Critical Care Case Report

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VOLUME 2 , ISSUE 2 ( March-April, 2023 ) > List of Articles


Coronavirus Disease 2019-associated Disseminated Histoplasmosis in Immunocompetent Host

Smita Sharma, Gyanendra Agrawal, Diksha D Yadav, Sharique Ahmed

Keywords : Coronavirus disease 2019, Histoplasmosis, Immunocompetent

Citation Information : Sharma S, Agrawal G, Yadav DD, Ahmed S. Coronavirus Disease 2019-associated Disseminated Histoplasmosis in Immunocompetent Host. 2023; 2 (2):40-43.

DOI: 10.5005/jp-journals-11006-0046

License: CC BY-NC 4.0

Published Online: 06-05-2023

Copyright Statement:  Copyright © 2023; The Author(s).


We hereby report the first case in the Indian subcontinent to the best of our knowledge of dual infection of disseminated histoplasmosis in an immunocompetent host with coronavirus disease 2019 (COVID-19) infection. We herein report a case of a 22-year-old COVID-19-positive immunocompetent male who presented with fever, breathing difficulty, pancytopenia, and skin exanthem. The bone marrow and skin biopsy established the diagnosis of disseminated histoplasmosis. The case was successfully treated with amphotericin and itraconazole. Diagnosis of opportunistic or coinfection infection in COVID-19 patients requires a high-index of suspicion, especially in immunocompetent patients.

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