Indian Journal of Critical Care Case Report

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VOLUME 1 , ISSUE 2 ( September-October, 2022 ) > List of Articles

CASE REPORT

Spontaneous Splenic Rupture in Chronic Myelomonocytic Leukemia Post G-CSF Administration

Promita Barua, Chandrashish Chakravarty, Soumya Bhattacharya, Lawni Goswami

Keywords : Acute abdomen, Chronic myelomonocytic leukemia, Granulocyte colony-stimulating factor, Hemoperitoneum, Shock, Splenic injury, Spontaneous splenic rupture

Citation Information : Barua P, Chakravarty C, Bhattacharya S, Goswami L. Spontaneous Splenic Rupture in Chronic Myelomonocytic Leukemia Post G-CSF Administration. 2022; 1 (2):46-47.

DOI: 10.5005/jp-journals-11006-0017

License: CC BY-NC 4.0

Published Online: 04-11-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Highlights Splenic rupture is a potentially life-threatening condition, often associated with trauma. Spontaneous splenic rupture (SSR) is very rare and is usually reported as secondary to some pathological conditions like infection (malaria, infectious mononucleosis), pancreatitis, sarcoidosis, or hematological malignancy. In this case report, we present an unusual presentation of SSR in a case of chronic myelomonocytic leukemia (CMML) who received granulocyte colony-stimulating factor (G-CSF) 10 days before presentation. Splenic rupture is one of the main causes of acute abdomen and should be considered in CMML or lymphoma. The history of G-CSF use is significant as it may cause SSR.


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