Highlights
Splenic rupture is a potentially life-threatening condition, often associated with trauma. Spontaneous splenic rupture (SSR) is very rare and is usually reported as secondary to some pathological conditions like infection (malaria, infectious mononucleosis), pancreatitis, sarcoidosis, or hematological malignancy. In this case report, we present an unusual presentation of SSR in a case of chronic myelomonocytic leukemia (CMML) who received granulocyte colony-stimulating factor (G-CSF) 10 days before presentation. Splenic rupture is one of the main causes of acute abdomen and should be considered in CMML or lymphoma. The history of G-CSF use is significant as it may cause SSR.
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