Indian Journal of Critical Care Case Report

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VOLUME 1 , ISSUE 1 ( July-August, 2022 ) > List of Articles

CASE REPORT

DRESS Syndrome in Trauma Intensive Care Unit

Aayush Kulshrestha, Yudhyavir Singh

Keywords : Drug reactions, Drug reaction with eosinophilia and systemic symptoms, Phenytoin, Registry of severe cutaneous adverse reactions

Citation Information : Kulshrestha A, Singh Y. DRESS Syndrome in Trauma Intensive Care Unit. 2022; 1 (1):28-30.

DOI: 10.5005/jp-journals-11006-0011

License: CC BY-NC 4.0

Published Online: 31-08-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe adverse drug reaction characterized by a range of clinical manifestations, including an extensive skin rash, fever, lymphadenopathy, eosinophilia, and visceral organ involvement. The prolonged latency period and heterogeneous clinical profile with overlapping symptoms make the diagnosis of DRESS challenging as it mimics many common presentations, though mortality constitutes about 10%. Here we report a postoperative case of decompression craniectomy with acetabulum fracture discharged on phenytoin therapy presented with fever, rash, and breathing difficulty, which was later diagnosed as DRESS.

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