Keywords :
Fever with rash, Leukemoid reaction, Scrub typhus
Citation Information :
Mouli TC, Patnaik R, Samal P, Pradhan S, Mishra SB. Leukemoid Reaction Associated with Scrub Typhus Infection: A Rare Case Report with a Review of Literature. 2022; 1 (1):23-25.
Scrub typhus is a tropical disease caused by the rickettsia group of obligate intracellular bacterium, Orientia tsutsugamushi, which usually presents as fever with rash. Scrub typhus has a wide spectrum of involvement which include acute kidney injury, thrombocytopenia, leukopenia, and hepatopathy. Leukemoid reaction is a reactionary proliferation of white blood cells secondary to stress or infection. Leukopenia is scrub typhus norm, but our patient developed a lymphocyte-predominant leukemoid reaction. The patient had hypofibrinogenemia and platelet dysfunction, which was detected early by rotational thromboelastometry (ROTEM) analysis. We are bringing forward a case of scrub typhus with a leukemoid reaction.
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